Research · In vitro
Inhibition of aflatoxin B1 genotoxicity and prevention of arsenic-induced cell transformation
Lu et al. · 2006 · Journal of Ethnopharmacology
Key finding
Spirulina extract inhibited the genotoxic effects of aflatoxin B1 and arsenic in human cell cultures. The effect was attributed to spirulina's antioxidant and anti-mutagenic properties rather than direct metal chelation.
Why this matters for consumers
Addresses a double-edged concern: spirulina can contain arsenic if grown in contaminated water, but it also appears to help mitigate arsenic's cellular damage. This does not mean spirulina is safe to take if it contains elevated arsenic — it means the intrinsic antioxidant properties provide partial protection against environmental toxins independent of spirulina's own purity.
Study limitations
In-vitro only; high concentrations used; does not translate directly to in-vivo arsenic exposure scenarios.
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New research, when it matters
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