Research · Randomised controlled trial
Spirulina supplementation improves lipid profile and oxidative stress in non-alcoholic fatty liver disease
Ismail et al. · 2015 · Arab Journal of Gastroenterology
Key finding
Spirulina at 1.5 g/day significantly reduced liver enzymes (ALT, AST), total cholesterol, LDL, triglycerides, and oxidative stress markers in NAFLD patients. Ultrasound assessment showed a reduction in fatty infiltration grade in the spirulina group.
Why this matters for consumers
The dose is very low (1.5 g/day) by study standards, yet produced clinically meaningful liver improvements. NAFLD is increasingly common; this is one of the few studies examining spirulina in a liver-specific population.
Study limitations
Single centre; dietary changes were not controlled; NAFLD diagnosis was ultrasound-based, not biopsy.
Related studies
Spirulina maxima prevents induction of fatty liver by carbon tetrachloride
Torres-Durán et al. · 2007
Antihyperlipidemic effects of spirulina in patients with type 2 diabetes
Mani et al. · 2000
Ergogenic and antioxidant effects of spirulina supplementation
Kalafati et al. · 2010
Anti-obesity and anti-inflammatory effects of spirulina in obese adults
Park et al. · 2008
New research, when it matters
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